{"id":58141,"date":"2016-09-20T14:00:40","date_gmt":"2016-09-20T12:00:40","guid":{"rendered":"http:\/\/novanews.co.za\/rooirose\/?p=58141"},"modified":"2017-05-15T14:22:49","modified_gmt":"2017-05-15T12:22:49","slug":"genetiese-toetsing-vir-medikasie","status":"publish","type":"post","link":"https:\/\/novanews.co.za\/rooirose\/genetiese-toetsing-vir-medikasie\/","title":{"rendered":"Genetiese toetsing vir medikasie"},"content":{"rendered":"

Medisyne moet jou gesond maak. Maar dit gebeur nie altyd nie, en nie almal word\u00a0gesond nie.<\/p>\n

“Variasies in ons gene, die bloudruk vir wie ons is, het \u2019n reuse-impak op ons elkeen se individuele reaksie op medikasie,” s\u00ea dr. Danny Meyersfeld, hoof van DNAlysis, een van die enkele maatskappye wat hierdie genetiese toetse plaaslik doen.<\/p>\n

 <\/p>\n

Risiko\u2019s en gevare van medisyne<\/h4>\n

Daar is vier algemeen negatiewe reaksies op medikasie, wat hoofsaaklik op ons genetiese profiel gebaseer is:<\/p>\n

1. Party van ons reageer nie<\/strong><\/p>\n

Medikasie soos Singulair<\/em> vir asma en ekseem is so goed as 100% suksesvol \u2026 maar net vir die 25% van mense wat \u2019n spesifieke genetiese basis vir hul allergie het. Vir die res is dit geld in die water. Net so met talle psigiatriese medikasies. Wat vir die een uitstekend is, werk nie vir \u2019n volgende een weer glad nie.<\/p>\n

2. Party van ons raak verslaaf\u00a0<\/strong><\/p>\n

Gewone kode\u00efen-pynpille is vir die meeste van ons veilig en verlig ons pyn baie doeltreffend. Maar \u2019n klein groepie mense is sogenaamde supermetaboliseerders. Hulle skakel \u2019n klein bietjie kode\u00efen om in superhoeveelhede, wat dan net soos morfien en hero\u00efen in die brein werk.<\/p>\n

3. Party van ons ontwikkel newe-effe<\/strong><\/p>\n

Ons kan almal \u2019n bietjie naarheid of ligte hoofpyn wat verby gaan, hanteer. Maar wat as jou bloeddrukmedikasie jou dood veroorsaak? Of as die medikasie om jou osteoporose om te keer, ly tot kaakkanker? Of as statiene spierpyne (rabdomeiolise) veroorsaak? DNAlysis s\u00ea 6-8% van mense wat in ons hospitale opgeneem word, het \u2019n negatiewe reaksie op medikasie \u2013 soveel as een uit elke 15\u00a0mense.<\/p>\n

4. Party van ons sterf<\/strong><\/p>\n

Selfs d\u00edt gebeur. Die medikasie-sterftesyfer in die VSA is \u2019n ysingwekkende 100\u00a0000 mense per jaar. Een bekende voorbeeld is dat mense wat sekere antidepressante begin gebruik in die eerste drie weke selfs meer depressief raak en \u2019n groter risiko op selfmoord loop.<\/p>\n

Ons wil geensins te kenne gee dat medikasie in die re\u00ebl gevaarlik is nie. G\u00e9\u00e9nsins nie. Alle voorskrifmedikasie in Suid-Afrika is deeglik getoets en word uitstekend beheer.\u00a0Maar, terselfdertyd verdien individuele reaksies ook erkenning. Tot dusver moes ons almal maar op die tref-en-trap manier uitvind of ons een van hulle is. En ja \u2026 met gevolge.<\/p>\n

Uiteindelik, s\u00ea dr. Meyersfeld, na dekades van navorsing, kan ons nou begin om ons kennis van gene en reaksies op medikasie bymekaar te bring en gebruik om te keer dat ons medikasie voorskryf wat gevaarlike fisieke of psigiese effekte het.<\/p>\n

Jy kan nou pro-aktief werk: in plaas van wag en sien wat werk, kan ons nou met genetiese toetse voorspel of \u2019n sekere soort\u00a0medikasie die regte en veiligste keuse is.<\/p>\n

Lees ook: Wat is IV-terapie?<\/a><\/p>\n

 <\/p>\n

Redes vir genetiese toetse vir medikasie<\/h4>\n

Die meeste probleme onstaan juis weens die gebruik van die algemeenste middels soos warfarin, psigiatriese medikasies en kode\u00efen-pynpille, s\u00ea dr. Meyersfeld. “Ons skryf hierdie pille voor vir van die algemeenste toestande, soos hartsiektes, psigiatriese toestande en pynbeheer.”<\/p>\n

Dus is die kanse goed dat ek en jy iewers vorentoe in ons lewens \u2019n medikasie gaan moet gebruik waarop ons nie goed reageer nie.\u00a0Gelukkig is genetiese toetsing vir medikasie net een maal nodig. Jou gene verander nie, en dus bly jou reaksie deur jou lewe konstant.\u00a0Aan die ander kant is farmakogenetika \u2019n jong veld wat beslis gaan uitbrei \u2013 wat beteken dat jy dalk vorentoe wel weer getoets sal word, soos wat meer gesofistikeerde toetse en nuwe medikasies ontwikkel.<\/p>\n

Dit sal nie \u2019n slegte idee wees as ons \u00e1lmal gaan nie. Maar prakties is dit nie moontlik nie. Op hierdie stadium maak dit vir die volgende mense sin om te toets:<\/p>\n

\u2022 Jy is pas met \u2019n toestand gediagnoseer waarvoor jy langtermyn medikasie gaan gebruik, soos epilepsie of ho\u00eb bloeddruk, en jy wil weet watter sal doeltreffend werk.<\/p>\n

\u2022 Jy ervaar newe-effekte van die tipiese medikasie en moet vasstel watter ander soorte beter werk, soos wat mense met ho\u00eb bloeddruk dikwels ervaar.<\/p>\n

\u2022 Jy reageer nie, en soek \u2019n doeltreffender alternatief. Dit kan lank neem om die regte medikasie vir iemand met epilepsie, aandagafleibaarheid en psigiatriese toestande soos depressie en bipol\u00eare depressie te identifiseer.<\/p>\n

\u2022 Jy moet \u2019n medikasie teen \u2019n baie ho\u00ebr as normale dosis gebruik. Genetiese toetsing kan vooraf uitwys hoe goed jou liggaam dit sal hanteer.<\/p>\n

Lees ook:\u00a0Moet jy verpersoonlikte hormoonpille vir die menopouse oorweeg?<\/a><\/p>\n

 <\/p>\n

Vir watter medisyne is genetiese toetse beskikbaar?<\/h4>\n

DNAlysis bied vier toetspanele aan: jy kan gaan vir die volledige genetiese toets, mygeneRx<\/em>, of vir enige van die panele waaruit dit bestaan, naamlik mycardioRx<\/em> vir hartlyers, mypsychRx<\/em> vir medikasie wat op die brein inwerk, en mypainRx<\/em> vir pynverwante medikasies.<\/p>\n

Die panele toets gesamentlik vir 150 medikasies, insluitend spierverslappers, bloedverdunners, pynstillers (NSAIDs, kode\u00efen en opo\u00efede), slaappille asook medikasie vir aandagafleibaarheid (AAHD), epilepsie, malaria, demensie, jig (gout<\/em>) en erektiele disfunksie. Die volledige lys is\u00a0hier\u00a0beskikbaar<\/a>.<\/p>\n

 <\/p>\n

Suid-Afrikaanse maatskappye wat genetiese toetsing doen<\/h4>\n

DNAlysis <\/a>spesialiseer in genetiese toetse om vas te stel watter tipe dieet moontlik die beste vir jou gaan werk, asook vir sportpotensiaal en reaksies op medikasie.<\/p>\n

Gknowmix<\/a> spesialiseer veral in die genetiese toetse om siektes te diagnoseer, soos hartsiektes, borskanker, afwykings in ystermetabolisme en sportbeserings. Buiten genetiese toetsing vir medikasie toets hulle ook potensiaal vir sportbeserings.<\/p>\n","protected":false},"excerpt":{"rendered":"

Genetiese toetse kan nou wys of \u2019n nuwe medisyne jou sal help of nie. Jy verwag nie om te sterf of verslaaf te raak aan medikasie nie, maar soms gebeur presies dit. Genetiese toetse wat jou waarsku is \u2019n reusestap vorentoe. Maar weet jou dokter daarvan? Deur Salom\u00e9 Delport<\/p>\n","protected":false},"author":19,"featured_media":59031,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2949,667],"tags":[6148,762,1657],"class_list":["post-58141","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-leef-gesond","category-gesondheid","tag-genetiese-toetsing","tag-borskanker","tag-allergie"],"acf":[],"yoast_head":"\nGenetiese toetsing vir medikasie | rooi rose<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/novanews.co.za\/rooirose\/genetiese-toetsing-vir-medikasie\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Genetiese toetsing vir medikasie | rooi rose\" \/>\n<meta property=\"og:description\" content=\"Genetiese toetse kan nou wys of \u2019n nuwe medisyne jou sal help of nie. 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Deur Salom\u00e9 Delport\" \/>\n<meta property=\"og:url\" content=\"https:\/\/novanews.co.za\/rooirose\/genetiese-toetsing-vir-medikasie\/\" \/>\n<meta property=\"og:site_name\" content=\"rooi rose\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/rooirose\/\" \/>\n<meta property=\"article:published_time\" content=\"2016-09-20T12:00:40+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2017-05-15T12:22:49+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/novanews.co.za\/rooirose\/wp-content\/uploads\/2016\/09\/Bloedtoets.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1000\" \/>\n\t<meta property=\"og:image:height\" content=\"750\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Salome Delport\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@rooi_rose\" \/>\n<meta name=\"twitter:site\" 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