Die Universiteit Stellenbosch (US) en die ho\u00ebtegnologiemaatskappy Enlightened Isotopes, \u2019n filiaal van ASP Isotopes, het \u2019n navorsingsvennootskap ter waarde van R8,5 miljoen aangegaan om \u2019n protokol te ontwikkel vir die skeiding van die ytterbium-176-isotoop om gebruik te word as \u2019n radiofarmaseutiese middel in kankerbehandeling.<\/p>\n\n\n\n
Isotoopproduserende maatskappye is w\u00eareldwyd op soek na alternatiewe tegnologie\u00eb omdat tradisionele bronne, meestal kernreaktors, die einde van hul lewensiklusse bereik. Rusland en China is tans die w\u00eareld se grootste verskaffers van isotope.<\/p>\n\n\n\n
Dr. Christine Steenkamp, \u2019n laserfisikus in die US se departement fisika, is sedert 2015 besig om ondersoek in te stel na die gebruik van lasergebaseerde resonansie-ionisasie as \u2019n tegniek om atoomisotope vir mediese gebruik te suiwer. Sy doen navorsing op die gebied van resonansie-ionisasie-spektroskopie \u2013 \u2019n uiters sensitiewe en hoogs selektiewe analitiese metingsmetode om individuele atome en molekule op te spoor. <\/p>\n\n\n\n
Steenkamp en haar span het reeds die tegniek suksesvol op sink-isotope toegepas, aangesien die produksie van suiwer sink-68 belangrik is vir die produksie van gallium-68 (wat in mediese PET- diagnostiese skanderings gebruik word). <\/p>\n\n\n\n
Sy s\u00ea die projek sal uit twee fases bestaan. \u201cGedurende die eerste fase sal ons ons bestaande toerusting en eksperimentele opstelling gebruik om hierdie spesifieke ytterbium-isotoop te bestudeer en te verstaan. Dit sal ons \u2019n beter begrip gee van die eksperimentele opstelling wat nodig is om hierdie isotoop op kommersi\u00eble skaal te beheer en te skei van die materiaal waarin dit natuurlik voorkom.\u201d<\/p>\n\n\n\n
Ytterbium is \u2019n skaars aard-chemiese element (Yb) wat natuurlik in erts voorkom. Een van sy sewe isotope, ytterbium-176, kan maklik na radioaktiewe lutetium-177 omgeskakel word, wat hoofsaaklik in die behandeling van prostaatkanker gebruik word. In kerngeneeskunde word isotope wat lae vlakke van bestraling vrystel, gebruik om kankerselle te teiken. <\/p>\n\n\n\n
Aangesien liggaamsweefsel, wat deur kanker geraak word, verhoogde selaktiwiteit het, sal die kankerselle m\u00e9\u00e9r van die radioaktiewe isotope absorbeer. Op hierdie wyse word kankerselle dus geteiken. <\/p>\n\n\n\n
Terapeutiese isotope is egter baie duur en kan tienduisende dollar per gram kos. En aangesien hierdie isotope slegs vir \u2019n kort tydperk radioaktief bly, moet hul naby hospitale vervaardig word.<\/p>\n\n\n\n
Prof. Pieter Neethling, direkteur van die Stellenbosch- Instituut vir Fotonika by die US en medenavorser van die projek, s\u00ea ho\u00eb vlakke van kundigheid en gespesialiseerde toerusting is voorvereistes vir die ontwikkeling van so \u2019n protokol. \u201cOns is baie opgewonde om te kan bydra tot die ontwikkeling van so \u2019n ho\u00ebtegnologie-isotoopverrykingsfasiliteit in Suid-Afrika.\u201d<\/p>\n\n\n\n
Josua Oosthuizen, projekbestuurder by Enlightened Isotopes en ASP Isotopes, s\u00ea hulle sien daarna uit om saam met \u2019n w\u00eareldklas-span by die US te werk. \u201cHoewel die werk tans op Yb-176 fokus, het ons \u2019n klomp mediese isotope in die pyplyn wat in die toekoms in vennootskap met die US-span ontwikkel sal word.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"
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